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Life Extension, Carnosine, 500 mg 60 Capsules
(LEF-01829)


Life Extension, Carnosine, 500 mg 60 Capsules
    
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Super Carnosine
500 mg 90 Vegetarian Capsules
Item Catalog Number: 01687

Carnosine is a multifunctional dipeptide made up of the amino acids beta-alanine and L-histidine. It is found both in food and in the human body. Long-lived cells such as nerve cells (neurons) and muscle cells (myocytes) contain high levels of carnosine.30 Muscle levels of carnosine correlate with the maximum life spans of animals. Carnosine has a number of antioxidant properties and has been shown to be an anti-glycating agent.31-37

This nutrient has the ability to suppress formation of advanced glycation end products (AGEs) and reactive oxygen species (ROS),38-41culprits in metabolic dysfunction and oxidative stress that can lead to age-related conditions.42-44Carnosine levels decline with age. Muscle levels decline 63% from age 10 to age 70, which may account for the normal age-related decline in muscle mass and function.45

Since carnosine acts as a pH buffer, it can keep on protecting muscle cell membranes from oxidation under the acidic conditions of muscular exertion. Carnosine enables the heart muscle to contract more efficiently through enhancement of calcium response in heart myocytes.46

Aging causes irreversible damage to the body’s proteins. One underlying mechanism behind this damage is glycation. Glycation involves the non-enzyme controlled cross-linking of proteins or lipids and sugars to form non-functioning structures in the body. The process of glycation can be superficially seen as unsightly wrinkled skin. Glycation is also an underlying cause of age-related neurologic, vascular, and eye problems.47-58 Carnosine is a unique dipeptide that can interfere with the glycation process.31-37

Benfotiamine, a derivative of thiamine (vitamin B1), provides additional protection against glycation reactions while guarding cells against the toxic effects of chronic glucose exposure. Even people with normal glucose levels encounter damaging sugar reactions over a lifetime. Benfotiamine protects against glucose-induced cell damage via several mechanisms.59-65

Supplement Facts

Serving Size 1 vegetarian capsule

Servings Per Container 90

Amount Per Serving

Thiamine (vitamin B1) (as thiamine HCl)

50 mg

L-Carnosine

500 mg

Benfotiamine

50 mg

Luteolin [from Pureloin™ and SMART™ ((Cynara cardunculus) extract (leaf)]

4 mg

Other ingredients: gelatin, vegetable cellulose (capsule), rice flour, ascorbyl palmitate.

Pureloin™ and SMART™ are trademarks of PharmaScience Nutrients, Inc., and are used here under license. All rights reserved worldwide.

Dosage and Use
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Take one capsule two to three times daily with or without food, or as recommended by a healthcare practitioner.

Warnings
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Keep out of reach of children.

-

Do not exceed recommended dose.

-

Do not purchase if outer seal is broken or damaged.

- If you have a bad reaction to product discontinue use immediately.
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When using nutritional supplements, please inform your physician if your are undergoing treatment for a medical condition or if you are pregnant or lactating.



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