The
benefits of plant polyphenols are well known to health enthusiasts.
These natural plant constituents block oxidative damage that lead to
inflammation and accelerated biological aging of tissues.
Recent
studies by three separate laboratories have concluded that polyphenols
extracted from apples extend life span in laboratory models by up to
12%. Apples and especially their skin, are rich in an array of
polyphenols. One particular major bioactive polyphenol, phloridzin,
found in the skin of the apple, has been shown to act as a powerful
agent against glycation and other destructive processes in the body.
Phloridzin also regulates cell to cell signaling and supports healthy
glucose levels in those already within normal range by inhibiting the
glucose-6-phosphatase enzyme.
Apple
polyphenols can slow triglyceride absorption from the intestine by
blocking pancreatic lipase, an enzyme specifically required to break
down triglyceride fats. Additional research has shown that apple
polyphenols can increase the protective antioxidant molecule
paraoxonase by as much as 23%, thereby inhibiting dangerous lipid
peroxidation and reducing an inflammatory cascade. Along with
phloridzin, apples contain chlorogenic acid. Chlorogenic acid supports
healthy glucose levels in those whose glucose levels are already within
normal range by inhibiting the glucose-6-phosphatase enzyme, and by
increasing some cellular mechanisms that are stimulated by insulin in
liver cells.
AppleWise
Polyphenol Extract is extracted from the highest quality organically
grown apples. Each 600 mg vegetable capsule contains 300 milligrams
apple polyphenols.
Consumer
note: Members taking supplements providing standardized pomegranate and
coffee bean extracts, along with antiglycating nutrients like
carnosine, benfotiamine and pyridoxal-5-phosphate may be deriving
similar benefits as those provided by apple polyphenols.
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