have identified specific biological mechanisms that cause aging people
to gain weight… no matter how little they eat. The problem was that
there was no way to circumvent the underlying factors that cause excess
body fat… until now! As you are about to learn, gaining control over
your body’s command signals is critical to maintaining a healthy weight.
is a hormone that tells our brain that we have consumed enough calories
and can stop eating. Leptin also induces a process whereby fat stored
in cells is broken down. As we age, our cells (including the appetite
control center in our brains) become “leptin resistant.” This means
that leptin is unable to effectively regulate body weight.
weight gain is characterized by the enlargement of existing adipocytes
(fat cells) that store too much fat. The size of fat cells is
controlled by gene transcription factors. Fat cell size is closely
related with adiponectin expression — with reduced adiponectin
expression in larger fat cells. In addition, gene transcription factors
help regulate adiponectin, and this crucial hormone is critical for
supporting insulin sensitivity.
enzyme called glycerol-3-phosphatedehydrogenase is critical for
synthesizing fatty acids in our bodies. Suppressing this enzyme helps
reduce the amount of glucose (sugar) in our bloodstream from being
converted into fatty acids.
loss utilizing diet modification, supplements, hormones or drugs
usually functions via a single mechanism. Adipocytes (fat cells), on
the other hand, possess numerous means to ensure their survival. An
extract from a West African plant called Irvingia has been shown to
help maintain healthy body weight in four ways:
Fat cells produce C-reactive protein, a pro-inflammatory compound that
leads to “leptin resistance. Overweight people given Irvingia have
lower levels of CRP, and therefore less CRP is able to block the
activity of leptin. Leptin is important in weight management because it
promotes the breakdown of fat in adipocytes and tells the brain to turn
off chronic hunger messages.
Large fat cells secrete less adiponectin, and adiponectin is a crucial
hormone that helps support insulin sensitivity as well as
cardiovascular health. Overweight people given Irvingia show markedly
increased adiponectin levels.
the Fat Converting Enzyme
An enzyme called glycerol-3-phosphate dehydrogenase facilitates the
conversion of glucose into triglycerides that increase adipocyte size.
Irvingia inhibits glycerol-3-phosphate dehydrogenase, thus reducing the
amount of glucose (sugar) that is converted to fat in the body.
In order for carbohydrates to be fully absorbed, they must be broken
down in the digestive tract by the amylase enzyme. Irvingia inhibits
amylase, and thus reduces the amount of ingested starches that will be
absorbed as sugar.
studies demonstrate the weight loss properties of Irvingia.1 In the largest placebo
controlled human study, those taking Irvingia lost 28 pounds over a
10-week period compared to only up to 3 pounds in the placebo group. The study participants did not
alter their diet.*
on impressive human data, a dose of 150 mg of Integra-Lean™ Irvingia
taken twice a day is all that was needed to achieve unprecedented
supplement should be taken in conjunction with a healthy diet and
regular exercise program. Results may vary.